Back To Top
ASCO™ Series 273 and 373 Pneumatic Pinch Valves
ASCO Series 273-373
The series 273 are 2-Way normally closed and normally open pressure-operated pinch valves designed for use with high-purity liquids in biotech applications.
The pneumatic pinch valve is also available as a 3-way normally closed and normally open valve, designed for chromatography applications. Hermetic separation of control mechanism and the fluid within the tubing prevents contamination, assuring maximum purity of liquids. Available in a large range of body sizes to accommodate a wide variety of tubing sizes. Typical applications include single-use bioreactors, Tangential Flow Filtration (TFF), and Chromatography skids.

ASCO Series 273 Pneumatic Pinch Valve

Play Video
ASCO™ Series 273 and 373 Pneumatic Pinch Valves


Valve Type
2-Way Normally Open (NO) and Normally Closed (NC)
Material of construction
2-Way: Anodized Aluminum and Stainless Steel
Tube Range (OD)
2-Way: 1/4", 3/8", 1/2", 3/4", 1"
Tube Material
Silicone, cflex374, 082 and Tygon
Tube Hardness
55 - 80 Shore A (Gamma Radiated)
Tube Media Pressure
Up to 90 PSI (up to 6 BAR), depending on size and tubing material
Air operating / Piloting pressure
70 PSI – 145 PSI (4.8 BAR – 10 BAR)
Ambient Temperature
32°F to 104°F (0°C to + 40°C)
T-Groove for switch contact
Feedback on valve position status (Ex. ASCO Series 494)
Inert Gases or Liquids


  • Innovative design
    • No contact with the process media
    • Easy insertion and removal of flexible tubing
  • Industry Leading Performance and Reliability
    • High tube pinching cycles
    • Better retention and protection of tubing during pinching cycles
  • Operator Safety
    • Easy to use built-in protective safety guard
    • Manual override allows for tube insertion removal without valve actuation
  • Unmatched Product Support
    • Local sales support and product specialists help find solutions to customer specific applications
    • Technical service and online support